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Creative Biolabs Produces Efficient Liposomal Formulations to Facilitate Drug Delivery

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Creative Biolabs Produces Efficient Liposomal Formulations to Facilitate Drug Delivery

February 22
00:35 2022
With a full understanding of the structure and properties of liposomes, Creative Biolabs improves the efficacy of different drugs by designing various liposome-based drug delivery formulations.

New York, USA – February 21, 2022 – In recent years, novel cancer treatments have been emerging with continuous following-up modifications. To reduce the side effects of conventional anticancer drugs, specifically chemotherapy agents, various nanomedicines, including viral nanoparticles, quantum dots, polymer nanomaterials, and liposomes have been applied, among which liposomes have the unique spherical nanoparticles structure as a combination of two aqueous and organic phases which allows the entrapment of both hydrophilic and hydrophobic agents and enhances the specificity, bioavailability, and biocompatibility properties of antitumor drugs. With a professional research team and mature technologies, Creative Biolabs is confident to provide high-quality liposomal formulations development services for the delivery of different drugs.

Liposome Encapsulated Small Molecule Drugs

Small molecule drugs are widely used in the diagnosis and chemotherapy of cancer, vaccinology, ophthalmology, pulmonology and other pathologies, but their therapeutic effects are limited by their fast clearance, poor biological distribution, low intracellular absorption rate and toxicity in vivo. Creative Biolabs optimizes small molecule drug delivery by loading them into liposomes in which hydrophobic molecules are inserted in the aqueous internal volume formed by lipid bilayers, and hydrophilic molecules in the aqueous center.

Liposome Encapsulated Protein or Peptide

The efficiency of protein encapsulation by liposomes depends on the interaction between protein and lipid bilayers. By controlling the lipid composition and concentration of liposomes, the encapsulation efficiency of protein or peptides can be increased to facilitate electrostatic interaction. Liposome encapsulated protein or peptide developed by Creative Biolabs can sustain release, prevent degradation, increase the tissue permeability of peptide or protein during drug delivery, and more importantly broaden the delivery mode of therapeutic protein or peptide into administration by parenteral, oral, pulmonary, nasal, ocular and transdermal routes.

Liposome Encapsulated Prodrug

Prodrug-based liposomes can respond intelligently to certain stimuli and release the desired drugs at the required time and place. Studies demonstrate that liposome formulations impair the metabolic reactions and protect the loaded compounds from catabolism, and in turn improve the efficacy of anticancer drugs. Creative Biolabs chooses the appropriate stimulus type and chemical modification in different situations to design satisfactory prodrug-based nanomedicines.

Liposome Encapsulated Nucleic Acids

In recent years, NA-based compounds have produced promising drug candidates for the treatment of various diseases but with some drawbacks including poor chemical and thermodynamic stability, high in vivo toxicity and high production cost. A well-designed liposomal delivery system by Creative Biolabs can reduce the toxicity and increase the efficacy of NA-based drugs.

Liposome-Based Adjuvant

As well-tolerated vehicles that can be easily functionalized to display other moieties on their surface, liposomes have been investigated as potential elements of immunomodulatory therapies for many years, including marketed vaccines for influenza (Inflexal®), Hepatitis A (Epaxal®), and recently malaria (Mosquirix). To promote strong and appropriate immune cell activation, Creative Biolabs designed easy-to-modify liposome-based adjuvants that can adapt to any antigen and produce effective and durable immune responses.

More information about liposome formulation development can be found at https://www.creative-biolabs.com/lipid-based-delivery.

About Creative Biolabs

As a liposome development service provider with years of experience, Creative Biolabs offers featured services for liposomal formulation development which includes objective evaluation, preparation method selection, drug release control, and almost every detailed section only to meet every client’s needs.

Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-830-6441
Country: United States
Website: https://www.creative-biolabs.com/lipid-based-delivery